Capt. Guillermo I. Carrillo was born in Mexico City, Mexico, and raised in Redondo Beach, California. He enlisted in the Navy in 1992 and served aboard USS Pasadena (SSN 752) where he deployed to U.S. Central Command in 1993. 

He was commissioned through the Broadened Opportunity for Officer Selection and Training program and graduated from the University of Southern California with a bachelor's in architecture in 2001. He winged as a naval flight officer in April 2003. 

Carrillo is a graduate of the Navy Fighter Weapons School and the Carrier Airborne Early Warning Weapons School. In 2016, he graduated from the Naval Postgraduate School with a master's in systems engineering management and product development.

Carrillo has completed multiple deployments in support of combat operations: Operations Desert Shield, Iraqi Freedom, Enduring Freedom, Iraqi Resolve and Freedom Sentinel. He has also supported Operation Unified Response providing Humanitarian Aid/Disaster Relief to the victims of the 2010 earthquake in Haiti.

His assignments include: two tours with Airborne Command and Control Squadron (VAW) 125 deploying on USS John F. Kennedy (CV 67), USS Dwight D. Eisenhower (CVN 69) and USS Carl Vinson (CVN 70) and department head with Airborne Command and Control Squadron (VAW) 121 deploying on Eisenhower. He has also commanded Airborne Command and Control Squadron (VAW) 116 and served as the operations officer of Commander Carrier Strike Group 9 deploying on USS Theodore Roosevelt (CVN 71).

Carrillo has completed a tour at Naval Strike Air Warfare Center as a weapons and tactics instructor at Carrier Airborne Early Warning Weapons School and as a member of the Hawkeye Tactical Analysis Team he helped Naval Air Systems Command develop the E-2D Advanced Hawkeye. 

Additional assignments include: Airborne Command and Control/Fleet Logistics Support assignments officer with the Navy Personnel Command; J35 Directorate, Joint Working Group Lead for Intelligence, Surveillance and Reconnaissance global force allocation with the Joint Chiefs of Staff; and chief staff officer for the Commander Airborne Command and Control Logistic Wing.

In January 2021, Carrillo reported the E-2/C-2 Airborne Command and Control Systems Program Office (PMA-231). He assumed command of PMA-231 as program manager in August 2024.